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500 feet beneath the ocean's surface, the U.S. ballistic missile submarine Colorado receives orders to fire its nuclear arsenal at Pakistan. Captain Marcus Chaplin (Andre Braugher) and XO Sam Kendal (Scott Speedman) question the orders and the Colorado comes under fire from another U.S. submarine. With their submarine crippled, the crew of the Colorado are forced to seek refuge on a nearby island. They must survive unprecedented odds as they work to unravel the conspiracy and clear their names.